Check our new paper in ACS Nano Journal about amplification-free mitochondrial DNA quantification

Mar 18

In our latest research, we introduce a solid-state nanopore method for label-free, amplification-free detection of mitochondrial DNA (mtDNA), a key biomarker for disease. Using machine learning and exonuclease digestion, we achieve high accuracy in distinguishing mtDNA from genomic DNA in biological samples. This approach offers picomolar sensitivity with minimal preparation, making it ideal for clinical diagnostics.

Read the full paper here

Solid-state NanoporesAmit Meller Group Technionbio-sensingbiomedical applicationsKarawan HalabiACS Nano

Nasab Halabi

Check our new paper in ACS Nano Journal about amplification-free mitochondrial DNA quantification

Check out our review in Analytical Chemistry on The Emergence of Nanofluidics for Single-Biomolecule Manipulation and Sensing

Noam presented his final PhD seminar entitled "Single-Molecule Protein Sensing for Early AMD Diagnosis”