Malak Hijazi presented her research in faculty Seminar title : “ Studying fragmentation distribution of cell free DNA(cfDNA) in healthy and sick patients using solid-state nanopores”

In her seminar, Malak discussed the use of solid-state nanopores to detect cell-free DNA (cfDNA) length variations, a promising approach for non-invasive disease monitoring through liquid biopsy.

Solid-state nanopores enable direct, label-free, single-molecule analysis of cfDNA fragment sizes without the need for amplification, avoiding biases common in qPCR and NGS. By analyzing ion-current signatures during translocation, this method reveals detailed size distributions, enhancing diagnostic accuracy. It offers a fast, cost-effective tool with strong potential for early detection and point-of-care use in oncology.

 Great work Malak!

Next
Next

Check out our review in Analytical Chemistry on The Emergence of Nanofluidics for Single-Biomolecule Manipulation and Sensing