Malak Hijazi presented her research in faculty Seminar title : “ Studying fragmentation distribution of cell free DNA(cfDNA) in healthy and sick patients using solid-state nanopores”
In her seminar, Malak discussed the use of solid-state nanopores to detect cell-free DNA (cfDNA) length variations, a promising approach for non-invasive disease monitoring through liquid biopsy.
Solid-state nanopores enable direct, label-free, single-molecule analysis of cfDNA fragment sizes without the need for amplification, avoiding biases common in qPCR and NGS. By analyzing ion-current signatures during translocation, this method reveals detailed size distributions, enhancing diagnostic accuracy. It offers a fast, cost-effective tool with strong potential for early detection and point-of-care use in oncology.
Great work Malak!