Zohar Rosenstock presented his research in a faculty seminar!

In his seminar, Zohar, an MSc student, shared his work on liquid biopsy using saliva for cancer diagnostics. He presented a novel biochemical assay that transforms raw saliva into detectable signals with solid-state nanopores (ssNPs), overcoming the challenges of low biomarker concentrations and chemical complexity.

Zohar’s approach integrates a filtration step to remove abundant proteins like Amylase and a custom affinity bead system to enrich specific cancer biomarkers, including CEA and CA-125. He validated the pipeline using VEGF as a model protein and demonstrated detailed characterization of the target biomarkers.

This technique opens the door to fast, precise, and noninvasive detection of endogenous biomarkers, with strong potential for next-generation patient screening and cancer diagnostics.

Great work, Zohar!