In the seminar, Ivy described a nanofluidic platform for simultaneously measuring the size and surface charge of individual small extracellular vesicles (sEVs) in physiological conditions. The approach combines electrokinetic confinement with single-particle tracking to characterize particles as small as 20 nm, well below the optical diffraction limit.
Her work highlights the potential of multiparametric single-particle analysis to uncover subtle biophysical signatures in extracellular-vesicle populations and support the discovery of future disease biomarkers.
Great work, Ivy!
