protein identification

Prof. Meller delivered the Joan van der Waals colloquium in Leiden University

On October 26, 2018, Prof. Meller delivered the Joan van der Waals colloquium in the Department of Physics, Leiden University, the Netherlands. The broadly accessed colloquium was entitled “Nanopore bio-sensing: past, present and future” and covered over 20 years of nanopore research towards DNA sequencing as well as recent developments leading to


Congratulations to Nitinun for the publication of her Chem Society Review paper

Proteins are the structural elements and machinery of cells responsible for a functioning biological architecture and homeostasis. Advances in nanotechnology are catalyzing key breakthroughs in many areas, including the analysis and study of proteins at the single-molecule level. Nanopore sensing is at the forefront of this revolution. This tutorial review, published on October 17, 2018, provides readers a guidebook and reference for detecting and characterizing proteins at the single-molecule level using nanopores. Specifically, the review describes the key materials, nanoscale features, and design requirements of nanopores. It also discusses general design requirements as well as details on the analysis of protein translocation. Finally, the article provides the background necessary to understand current research trends and to encourage the identification of new biomedical applications for protein sensing using nanopores.