Prof. Meller delivered the Joan van der Waals colloquium in Leiden University

On October 26, 2018, Prof. Meller delivered the Joan van der Waals colloquium in the Department of Physics, Leiden University, the Netherlands. The broadly accessed colloquium was entitled “Nanopore bio-sensing: past, present and future” and covered over 20 years of nanopore research towards DNA sequencing as well as recent developments leading to

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Titanium dioxide Nanopores for low background sensing

In a recent publication (ACS Nano, November 2018, DOI: 10.1021/acsnano.8b07055) we showed that thin titanium dioxide membranes produce negligible photoluminescence background as compared to silicon nitride membranes of same thickness. This discovery permits electrooptical sensing in nanopores with much improved signal-to-background ratio, allowing us to use it for sensing and discrimination among labelled DNA strands as well as polypeptides for the first time.

Tal Gilboa wins 'Best Poster Presentation' in Nano.IL.2018 conference

The Nano.IL conference is the premier international annual meeting in Nanosciences and Nanotechnology in Israel. On October 11, 2018, our Ph.D. student, Tal Gilboa, won “Best Poster Presentation”, among hundreds of participants. In the poster, she presented her work on Single Molecule Electro-optical Sensing in Solid-state Nanopores.

Congratulations to Nitinun for the publication of her Chem Society Review paper

Proteins are the structural elements and machinery of cells responsible for a functioning biological architecture and homeostasis. Advances in nanotechnology are catalyzing key breakthroughs in many areas, including the analysis and study of proteins at the single-molecule level. Nanopore sensing is at the forefront of this revolution. This tutorial review, published on October 17, 2018, provides readers a guidebook and reference for detecting and characterizing proteins at the single-molecule level using nanopores. Specifically, the review describes the key materials, nanoscale features, and design requirements of nanopores. It also discusses general design requirements as well as details on the analysis of protein translocation. Finally, the article provides the background necessary to understand current research trends and to encourage the identification of new biomedical applications for protein sensing using nanopores.

Welcome Dr. Xander van-Kooten - a new postdoc in our lab!

A big welcome to Dr. Xander van-Kooten, who recently joined us from the IBM Zurich labs. Xander completed his B.Sc. in Electrical Engineering at the Delft Technical University, before moving to EPFL (Lausanne, Switzerland), where he started his graduate studies. He then moved to the IBM labs in Zurich for his Ph.D. research.

Xander’s Ph.D. work focused mainly on microfluidics and he is joining our nanopore sequencing team. Welcome Xander!