Congratulation to Shilo Ohayon!
Shilo Ohayon, a Ph.D. student in our group, won the best poster presentation at the NanoIL 2021.
His poster title : "On-chip protein separation with single-molecule resolution using SDS-PAGE nanochannels”.
The research's main aim is to identify and quantify proteins at a single molecule level using nanochannels. The use of nanochannel allows real-time tracking of the translocating proteins by a computer vision algorithm. The data obtained from each protein enables the identification of the protein and, by that, the whole sample. In the future, this technology could manifest faster and more efficient identification of proteins in biological and clinical samples and eventually will help in more accurate diagnostics.
Congratulations to Eran on his ACS Nano paper reporting fast and deterministic nanopore drilling
In a latest publication, we develop a custom algorithm (called NLDA) and software to deliver a deterministic fashion of sub-nanopore laser drilling. We provide a full recipe to obtain the fabricated pores with a preset diameter (error) in less than two minutes. The in situ technique enables instant protein sensing following the nanopore formation. Our findings bring insights into the laser-drilled nanopore 3D shape, which contributes to the sensor’s biomolecule capture capabilities.
The lab perspective paper on the emerging field of single-molecule protein identification is out on Nature Methods
Single-cell profiling methods have had a profound impact on the understanding of cellular heterogeneity. While genomes and transcriptomes can be explored at the single-cell level, single-cell profiling of proteomes is not yet established. Here we describe new single-molecule protein sequencing and identification technologies alongside innovations in mass spectrometry that will eventually enable broad sequence coverage in single-cell profiling. These technologies will in turn facilitate biological discovery and open new avenues for ultrasensitive disease diagnostics.
Dr. Navneet Chandara Verma won the Council for Higher Education & IASH Fellowship Program for International Postdoctoral Researchers.
The Council for Higher Education in Israel and the Israel Academy of Sciences and Humanities (IASH) are pleased to announce a new excellence fellowship program for outstanding international postdoctoral researchers. The new program signifies Israel’s commitment to international scientific exchange and to the advancement of world-class research in Israeli universities
Dr. Navneet Chandra Verma, a postdoc fellow in our lab, won the fellowship for two years. Congratulations Navneet!
Dr. Navneet Chandra Verma
The lab's research on Single Protein Sensing is featured in the Israel Precision Medicine Program website
Our paper entitled: "On‑chip protein separation with single‑molecule resolution” that was published recently in Scientific Reports, was featured on the Israel Science Foundation Israel Precision Medicine Program (ISF IPMP) website.
In this project, our protein sensing technology will be used to identify protein biomarkers associated with Age-Related Macular Degeneration (AMD) disease in collaboration with researchers at Hadassah medical center in Jerusalem, Israel. Our Ph.D. team including Navneet Verma, Postdoctoral fellow, Shilo Ohayon, Ph.D. student, and Noam Freundlich, MSc student continue to promote the research in the project.
Congratulations to Dr. Navneet Chandra Verma for winning the INYAS Annual Award 2020 for Best PhD thesis in the area of carbon materials
Dr. Navneet Chandra Verma, a postdoc fellow in our lab, won the INYAS Annual Award 2020 for Best PhD thesis in the area of carbon materials. Congratulations Navneet!
