Neeraj presented his final PhD seminar entitled "Fingerprinting proteins one by one using nanopore biosensors"
In his seminar, he talked about the potential of using heat denaturation and the anionic surfactant sodium dodecyl sulfate (SDS) to facilitate the electrokinetic single-molecule nanopore. Sensing of unfolded proteins. Also talked about, the characterization of voltage-dependent translocation dynamics of proteins through sub-5 nm solid-state nanopores, employing SDS concentrations below the critical micelle concentration.
Prof. Meller delivers the Inaugural Speech at FARC 2024 conference in IIT Mandi, India.
Professor Meller recently attended the FARC 2024 conference (International Conference on Fundamental and Advanced Research in Chemistry) held at the Indian Institute of Technology Mandi, H.P., India. At this esteemed event, Prof. Meller was honored with the inaugural speech, marking a significant recognition of his groundbreaking contributions to the field of chemistry.
The FARC 2024 conference gathered leading researchers, scholars, and industry experts from around the globe to discuss the latest advancements and innovations in chemistry.
for more information about the FARC 2024 conference click here.
Meller lab team new paper in Advanced Materials journal
Full-Length Single Protein Molecules Tracking and Counting in thin Silicon Channels
In this paper, we introduce a single-molecule method for parallel protein separation and tracking, yielding multi-dimensional and are electrophoretically separated by their mass/charge in custom-designed thin silicon channel with subwavelength height. This approach allows us to analyse thousands of individual proteins within a few minutes by tracking their motion during the migration. We demonstrate the power of the method by quantifying a cytokine panel for host-response discrimination between viral and bacterial infections.
Check out the recent highlight of Our Nano letters paper featured in Advance in Engineering
Surfing the Nano Wave: Dramatic Leap in DNA Sensing with Surfactant-Coated Nanopores
The online platform of Advances in Engineering has showcased our recent Nano Letters article, titled "Over 30-Fold Enhancement in DNA Translocation Dynamics through Nanoscale Pores Coated with an Anionic Surfactant''.
Read the highlight here
Read the paper here
Neeraj Soni talk at Indian Institute of Technology Mandi
Neeraj Soni, PhD student in Meller lab visited IIT Mandi and presented his PhD work , in which he talked about the feasibility of whole protein identification and sequencing through sub 5nm solid state nanopore.
Neeraj extensively discussed the biophysical characteristics associated with the single-file translocation of whole proteins, underscoring its importance in contrast to traditional methods. Additionally, he delved into inventive strategies for regulating the dynamics of the translocating molecule as it passes through nanopores.
Welcoming our new PhD student Rohan Lamba
Today we welcomed Rohan Lamba to our lab. Rohan Lamba is a new PhD student in our lab. he completed his MSc degree in Chemistry from Indian Institute of Technology (IIT) Mandi. He will be joining our Nanopore team.
We keep on smiling, hoping for great new year 2024.
