Amit Meller Group Technion

Meller lab team new paper in Advanced Materials journal

Full-Length Single Protein Molecules Tracking and Counting in thin Silicon Channels

In this paper, we introduce a single-molecule method for parallel protein separation and tracking, yielding multi-dimensional and are electrophoretically separated by their mass/charge in custom-designed thin silicon channel with subwavelength height. This approach allows us to analyse thousands of individual proteins within a few minutes by tracking their motion during the migration. We demonstrate the power of the method by quantifying a cytokine panel for host-response discrimination between viral and bacterial infections.

Check the onilne paper

Check out the recent highlight of Our Nano letters paper featured in Advance in Engineering

Surfing the Nano Wave: Dramatic Leap in DNA Sensing with Surfactant-Coated Nanopores

The online platform of Advances in Engineering has showcased our recent Nano Letters article, titled  "Over 30-Fold Enhancement in DNA Translocation Dynamics through Nanoscale Pores Coated with an Anionic Surfactant''. 

Read the highlight here

Read the paper here

Happy Holidays from the Meller lab family to Yours.

Dr. Yulia Marom and Dr. Navneet C. Verma from our lab. present the fabrication process of our sensor that can detect single biological molecules - in a 'Holidays' edition.
The tiny sensor (only 4x4 mm), is made of a thin silicon piece that is coated with photoresist (the red material in the video), and the special pattern is exposed to UV light by digital lithography.

The development of the sensor is a significant breakthrough in the early diagnosis of diseases, allowing early treatment and saving lives.